![]() The ratio of antigen concentration to viral load in samples with ≥10 3 copies/ml was comparable in symptomatic and asymptomatic individuals ( P = 0.58). ![]() ![]() All samples with ≤10 3 copies/ml were antigen negative. The overall sensitivity and specificity of the Liaison antigen test compared to RT-PCR were 65.7% (95% confidence interval, 58.9% to 71.9%) and 100% (CI, 97.8% to 100%). Equivocal results were considered negative. Samples were tested on Liaison XL according to the manufacturer’s instructions. Leftover reverse transcription-PCR (RT-PCR) positive ( n = 204) and negative ( n = 210) nasopharyngeal samples were randomly selected among fresh routine samples collected from patients consulting their GPs. We evaluated the quantitative DiaSorin Liaison severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigen test in symptomatic and asymptomatic individuals consulting their general practitioners (GPs) during a period of stable intense virus circulation (213/100,000 habitants per day).
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